Probiotic production
Contract manufacturing of probiotics
JSC «Vector-BiAlgam» offers full-cycle contract manufacturing services - from the substance to the finished product. The basis of most biotechnologies is the producer strain. JSC «Vector-BiAlgam» has more than 80 production strains of probiotics, which allows you to create many effective biological products.
The company can carry out the following processes under controlled conditions:
- Fermentation
- Immobilization
- Aseptic filling
- Lyophilization
- Mixing dry ingredients
- Capsule filling
- Packing in sachets
The company also offers the possibility of cooperation on the «in-bulk» system.
Our production capabilities
- Liquid forms of dietary supplements and bioproducts in vials or bottles;
- Solid forms of probiotics and symbiotics: tablets, powders in sachets, capsules.
Production capacity
- Obtaining liquid biomass by deep fermentation - up to 10 thousand l/month;
- Aseptic filling of liquid forms of probiotics - up to 300 thousand vials/month;
- Obtaining dry biomass by lyophilization - up to 40 kg/month;
- Production of capsules with probiotics - up to 500 thousand pieces/month;
- Sterile enzymatic bacterial lysates — up to 600 l/month.
Our advantages
- Modern production sites licensed for compliance with GMP and HACCP standards;
- Integrated QMS (quality management system), experienced and highly qualified personnel;
- Possibility of manufacturing both experimental and industrial series;
- Flexible pricing policy.
Development and contract manufacturing of multicomponent probiotics and synbiotics consists of the following main stages:
— Creation of a selective microbial base of the drug from different strains of bacteria-probiotics. The stage is complicated by the necessary creation of conditions for the ecological and physiological compatibility of bacteria. Requires multiple cultivation of consortiums with culling parameters: titer, safety, activity.
— Selection and introduction of prebiotic components into the preparations: for example, lactulose (stimulates the growth of bifidus and lactobacilli), vitamin C (participates in redox processes), MCC (removal of toxins and radionuclides). It is necessary to solve the problem of incompatibility of components.
— Optimization of technological processes: fermentation, freeze drying, mixing, encapsulation.
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